'Edited by a well known teacher, this issue brings out the recent advances in many emerging and important aspects of clinical practice:oBiochemical, imaging and clinical monitoring of early pregnancy oConcept of PUL (Pregnancy of Unknown Location) oBearings of excess and low volume of liquor amnii on imaging oRecently understood condition of hyperhomocystinemia for its obstetric bearings oManagement of critical condition of fetal asphyxia oApplication of prostaglandins beyond obstetric interventions oA case for taking a look again at vacuum delivery oApplication of 3D USG in gynecology practice oRecent advances in managing the refractory challenge of azoospermia oHow to reduce complications with laparoscopic surgery oIntrauterine progesterone systems, the current "in thing" oLatest information on cervical cancer vaccine.